GO_REF:0000002

Gene Ontology annotation through association of InterPro records with GO terms

Several annotations derived from IPR003852 (KdpD N-terminal sensor domain) incorrectly assign kinase activity to a sensory domain

GO_REF:0000043

Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping

Keywords "Kinase", "Transferase", and "Ion transport" led to over-annotations
The protein name containing "histidine kinase domain" was incorrectly interpreted as the protein having kinase activity

GO_REF:0000117

Electronic Gene Ontology annotations created by ARBA machine learning models

Cytoplasm annotation is appropriate for the cytoplasmic portions of this membrane-associated protein

GO_REF:0000118

TreeGrafter-generated GO annotations

GO_REF:0000120

Combined Automated Annotation using Multiple IEA Methods

Phosphorelay signal transduction system annotation is appropriate
Phosphorelay sensor kinase activity annotation is incorrect due to lack of catalytic domains

DOI:10.1371/journal.ppat.1003201

The KdpD/KdpE Two-Component System: Integrating K+ Homeostasis and Virulence

PMID:15077118

The genome sequence of the anaerobic, sulfate-reducing bacterium Desulfovibrio vulgaris Hildenborough

file:DESVH/Q725T9/Q725T9-deep-research-falcon.md

Deep research report on DVU_3336 (Q725T9) function

DVU_3336 is located within the kdp locus of DvH between kdpD and the structural kdpFABC genes

"DVU_3336 is located within the kdp locus of DvH. Operon maps in DvH position DVU_3336 between kdpD and the structural kdpFABC genes"
The conserved histidine kinase catalytic domains are on the adjacent DVU3335 gene, not DVU_3336

"In DvH, the conserved histidine kinase catalytic domains are explicitly assigned to the adjacent DVU3335 gene"

UniProt:Q725T9

UniProt entry for Q725T9 (DVU_3336)

DVU_3336 contains KdpD N-terminal sensor domain and UspA domain

"Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal"