Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
The yeast nuclear pore complex: composition, architecture, and transport mechanism.
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The GOA nucleolus IDA annotation traces to the Rout et al. 2000 nuclear pore complex proteomics paper. The cached full text never names Rrb1 or YMR131C; what it does say is that the NPC-enriched fraction contained nuclear and nucleolar components that may be contaminants or in transit. That is the quoted sentence, and it is the basis for treating this IDA as weak support for a nucleolar location rather than direct evidence for this protein.
"These include numerous nuclear and nucleolar components, which may have contaminated the fraction, or were perhaps caught in transit across the NPC."
A yeast homolog of chromatin assembly factor 1 is involved in early ribosome assembly.
High-definition macromolecular composition of yeast RNA-processing complexes.
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High-throughput interaction data place Rrb1 in RNA-processing/ribosome-biogenesis complexes but do not define a specific molecular function beyond generic binding.
"Some of the pre-rRNA-processing complexes that were obtained are discrete sub-complexes of those previously described. Among these, we identified the IPI complex required for proper processing of the ITS2 region of the ribosomal RNA primary transcript."
Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
Co-translational capturing of nascent ribosomal proteins by their dedicated chaperones.
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Rrb1 selectively captures nascent Rpl3 and functions as a dedicated ribosomal protein chaperone.
"Affinity purification of four chaperones (Rrb1, Syo1, Sqt1 and Yar1) selectively enriched the mRNAs encoding their specific ribosomal protein clients."
The social and structural architecture of the yeast protein interactome.
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Interactome data provide broad physical-interaction support but are too generic for accepting protein binding as the functional annotation.
"The social and structural architecture of the yeast protein interactome."
Falcon deep research report on RRB1
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Falcon synthesis identifies Rrb1 as a nuclear/nucleolar Rpl3-handling factor required for early large-subunit biogenesis.
"RRB1 encodes an essential, nuclear/nucleolar WD-repeat protein (Rrb1p) that binds ribosomal protein L3 (Rpl3) and is required for early large (60S) subunit biogenesis."
PANTHER family PTHR45903 metadata
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RRB1 is in the glutamate-rich WD-repeat PANTHER family, with yeast RRB1 in subfamily PTHR45903:SF1.
"Some family members are implicated in ribosome biogenesis, specifically in the early assembly of the 60S ribosomal subunit, by targeting ribosomal protein L3 onto precursor rRNA."