GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
PMID:10581176
Induced expression, localization, and chromosome mapping of a gene for the TBP-interacting protein 120A.
PMID:12504025
NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases.
PMID:12504026
CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex.
PMID:12609982
TIP120A associates with cullins and modulates ubiquitin ligase activity.
PMID:15537541
Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases.
PMID:16861300
Regulation of neddylation and deneddylation of cullin1 in SCFSkp2 ubiquitin ligase by F-box protein and substrate.
PMID:17290223
Impaired DNA damage checkpoint response in MIF-deficient mice.
PMID:18826954
SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation.
PMID:19056867
Large-scale proteomics and phosphoproteomics of urinary exosomes.
PMID:19946888
Defining the membrane proteome of NK cells.
PMID:20458337
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
PMID:21145461
Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics.
PMID:21249194
Regulation of cullin RING E3 ubiquitin ligases by CAND1 in vivo.
PMID:21630459
Proteomic characterization of the human sperm nucleus.
PMID:22405651
The glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin RING ligase-mediated turnover of Fbw7.
PMID:23533145
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
PMID:24192928
Oncogenic function of SCCRO5/DCUN1D5 requires its Neddylation E3 activity and nuclear localization.
PMID:25435324
Structural mechanism of nuclear transport mediated by importin β and flexible amphiphilic proteins.
PMID:26030138
Identification of Novel Proteins Co-Purifying with Cockayne Syndrome Group B (CSB) Reveals Potential Roles for CSB in RNA Metabolism and Chromatin Dynamics.
PMID:26496610
A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
PMID:26906416
Characterization of the mammalian family of DCN-type NEDD8 E3 ligases.
PMID:27542266
DCUN1D3 activates SCFSKP2 ubiquitin E3 ligase activity and cell cycle progression under UV damage.
PMID:30021884
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei.
PMID:34591642
A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity.
PMID:40205054
Multimodal cell maps as a foundation for structural and functional genomics.
Reactome:R-HSA-5691131
CANDI binds CUL1
Reactome:R-HSA-6798748
Exocytosis of secretory granule lumen proteins
Reactome:R-HSA-6800434
Exocytosis of ficolin-rich granule lumen proteins
Reactome:R-HSA-8955241
CAND1 binds cytosolic CRL E3 ubiquitin ligases
Reactome:R-HSA-8955245
CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus
Reactome:R-HSA-8955285
COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex
Reactome:R-HSA-8955289
COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes
file:human/CAND1/CAND1-uniprot.txt
CAND1 UniProtKB record (Q86VP6)
file:human/CAND1/CAND1-notes.md
Manual CAND1 curation notes