GO_REF:0000002

Gene Ontology annotation through association of InterPro records with GO terms

GO_REF:0000108

Automatic assignment of GO terms using logical inference, based on on inter-ontology links

GO_REF:0000118

TreeGrafter-generated GO annotations

GO_REF:0000120

Combined Automated Annotation using Multiple IEA Methods

PMID:9286988

Identification of the fliI and fliJ components of the Caulobacter flagellar type III protein secretion system.

fliI and fliJ form a class II flagellar operon. fliI mutants block flagellar assembly at an early stage and are non-motile. FliI is found in the cytoplasm and associated with the membrane. Conserved ATP-binding motif residues are required.

PMID:8943245

Enzymatic characterization of FliI. An ATPase involved in flagellar assembly in Salmonella typhimurium.

Salmonella FliI (ortholog) is a Mg2+-dependent ATPase that is insensitive to F-, V- and P-type ATPase inhibitors. Walker mutants block flagellar assembly.

PMID:17202259

Structural similarity between the flagellar type III ATPase FliI and F1-ATPase subunits.

The Salmonella FliI crystal structure resembles F1 alpha/beta, which explains the homology-based ATP synthase labels.

PMID:21278755

Common architecture of the flagellar type III protein export apparatus and F- and V-type ATPases.

FliJ is similar to the gamma-subunit coiled coil and binds the centre of the FliI hexamer ring.

PMID:18216858

Distinct roles of the FliI ATPase and proton motive force in bacterial flagellar protein export.

ATP hydrolysis by FliI releases the FliH-FliI escort after substrate entry into the gate. The PMF drives translocation.

PMID:18216859

Energy source of flagellar type III secretion.

The flagellar secretion apparatus is a proton-driven protein exporter. ATP hydrolysis by FliI is not essential for export.

PMID:21934659

An energy transduction mechanism used in bacterial flagellar type III protein export.

The export gate complex is a proton-protein antiporter. The FliH-FliI complex brings about FliJ-FlhA binding, which turns the gate into an efficient delta-psi-driven exporter.

PMID:29946050

In Vitro Reconstitution of Functional Type III Protein Export and Insights into Flagellar Assembly.

In inverted membrane vesicles, export needs Mg-ATP, FliJ and FliH2/FliI. ATP hydrolysis by FliI can drive some export without PMF, and FlhA has ion-channel activity.

file:CAUVC/fliI/fliI-deep-research-falcon.md

Falcon deep research report for Caulobacter FliI