Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

GO_REF:0000033

Annotation inferences using phylogenetic trees

GO_REF:0000044

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

GO_REF:0000107

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

PMID:18752060

The d subunit plays a central role in human vacuolar H(+)-ATPases.

Human V-ATPase F subunit directly interacts with d1 and d2 V0 subunits; F and D are pulled down by d1/d2 from human kidney membrane; confirmed direct D-F and F-d interactions; F forms part of the central stalk.

PMID:19056867

Large-scale proteomics and phosphoproteomics of urinary exosomes.

ATP6V1F detected in urinary exosomes by mass spectrometry.

PMID:19199708

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).

ATP6V1F detected in parotid gland exosome proteome.

PMID:32001091

Structure and Roles of V-type ATPases.

Comprehensive review of V-ATPase structure; F subunit is part of central rotor.

PMID:32296183

A reference map of the human binary protein interactome.

ATP6V1F detected in binary interactome map.

PMID:33065002

Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly.

Cryo-EM structures of complete human V-ATPase; F subunit resolved as part of the central DF rotor at near-atomic resolution.

PMID:33961781

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.

ATP6V1F detected in proteome-scale interactome study.

PMID:35271311

OpenCell: Endogenous tagging for the cartography of human cellular organization.

ATP6V1F localization mapped by endogenous tagging.

PMID:8581736

Cloning, sequencing and expression of a novel cDNA encoding human vacuolar ATPase (14-kDa subunit).

Human V-ATPase F subunit (14 kDa) cloned from fetal brain; ubiquitous expression in human tissues; high sequence conservation with insect orthologs.

Reactome:R-HSA-1222516

Intraphagosomal pH is lowered to 5 by V-ATPase

Reactome:R-HSA-5252133

ATP6AP1 binds V-ATPase

Reactome:R-HSA-74723

Endosome acidification

Reactome:R-HSA-917841

Acidification of Tf:TfR1 containing endosome

Reactome:R-HSA-9639286

RRAGC,D exchanges GTP for GDP

Reactome:R-HSA-9640167

RRAGA,B exchanges GDP for GTP

Reactome:R-HSA-9640168

v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine

Reactome:R-HSA-9640175

v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine

Reactome:R-HSA-9640195

RRAGA,B hydrolyzes GTP

Reactome:R-HSA-9645598

RRAGC,D hydrolyzes GTP

Reactome:R-HSA-9645608

v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1

Reactome:R-HSA-9646468

mTORC1 binds RHEB:GTP