tpi1 (S. pombe, UniProt P07669, SPCC24B10.21) notes

Role in module emp_glycolysis: triose-phosphate isomerase step (EC 5.3.1.1); S. cerevisiae counterpart TPI1.

Evidence

• Reaction GAP <-> DHAP [UniProt:P07669 "Reaction=D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate;"].
• Cloned by complementation of S. cerevisiae tpi1 PMID:3912263 (abstract only; the paper is mainly about transcription start sites).
• Cytosol by ORFeome screen PMID:16823372.

Curation decisions

• IGI to obsolete GO:0061621 -> MODIFY to GO:0006096.
• GO:0046166 G3P biosynthetic process (IBA) kept non-core, as for S. cerevisiae TPI1.

GO-CAM note

• The PomBase glycolysis model 663d668500002302 contains two tpi1 activity nodes (663d668500002432 and 68b0f0d000002382), both triose-phosphate isomerase activity in cytosol part_of GO:0061621; apparent duplicate.