Gene Ontology annotation through association of InterPro records with GO terms

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Gene Ontology annotation based on curation of immunofluorescence data

Electronic Gene Ontology annotations created by ARBA machine learning models

Crystal structure of the clathrin adaptor protein 1 core.

Mutations in the gene encoding the Sigma 2 subunit of the adaptor protein 1 complex, AP1S2, cause X-linked mental retardation.

Mutations in the AP1S2 gene encoding the sigma 2 subunit of the adaptor protein 1 complex are associated with syndromic X-linked mental retardation with hydrocephalus and calcifications in basal ganglia.

Clinical, cellular, and neuropathological consequences of AP1S2 mutations: further delineation of a recognizable X-linked mental retardation syndrome.

AP-1/sigma1B-adaptin mediates endosomal synaptic vesicle recycling, learning and memory.

Conservation and diversification of dileucine signal recognition by adaptor protein (AP) complex variants.

Cell type-specific Rab32 and Rab38 cooperate with the ubiquitous lysosome biogenesis machinery to synthesize specialized lysosome-related organelles.

AP1S2 is mutated in X-linked Dandy-Walker malformation with intellectual disability, basal ganglia disease and seizures (Pettigrew syndrome).

σ1B adaptin regulates adipogenesis by mediating the sorting of sortilin in adipose tissue.

AP-1/σ1B-Dependent SV Protein Recycling Is Regulated in Early Endosomes and Is Coupled to AP-2 Endocytosis.

A proteome-scale map of the human interactome network.

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.

AP-1/σ1A and AP-1/σ1B adaptor-proteins differentially regulate neuronal early endosome maturation via the Rab5/Vps34-pathway.

Architecture of the human interactome defines protein communities and disease networks.

An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders.

A reference map of the human binary protein interactome.

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.

Identification and characterization of novel clathrin adaptor-related proteins.

Degradation of MHC I Complex

Formation of MHC I:Nef:AP-1:PACS-1 Complex

Transport of MHC I:Nef:AP-1:PACS-1 Complex

TGN-lysosomal vesicle coat assembly

Translocation of TGN-lysosome vesicle to lysosome

TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome

trans-Golgi Network Coat Assembly

Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture

trans-Golgi Network Vesicle Scission

trans-Golgi Network Derived Vesicle Uncoating

trans-Golgi Network Derived Lysosomal Vesicle Uncoating

trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly

trans-Golgi Network Lysosomal Vesicle Scission

Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture On Lysosome Vesicle Destined Golgi Membrane

CLAT:AP1:CLVS bind PI(3,5)P2

Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex

UniProtKB record P56377 (AP1S2_HUMAN), entry version 215

AP1S2 (sigma1B) sequence analysis

Affinage mechanistic annotation for AP1S2 (human)