ACAP2 WITH/FROM resolution and domain-architecture check

Generated by resolve_withfrom.py from live API responses. Re-run with uv run resolve_withfrom.py to regenerate; values may change as the underlying databases are updated.

Reference: human ACAP2

Every WITH/FROM identifier in ACAP2-goa.tsv

WITH/FROM resolves to organism length ArfGAP domain? supports
AGI_LocusCode:AT5G13300 Q5W7F2 AGD3_ARATH (AGD3) Arabidopsis thaliana 827 yes GO:0005096 (IBA), GO:0005886 (IBA)
AGI_LocusCode:AT5G61980 Q9FIT8 AGD1_ARATH (AGD1) Arabidopsis thaliana 828 yes GO:0005886 (IBA)
FB:FBgn0004133 see notes below Drosophila melanogaster ? n/a GO:0030036 (IBA)
InterPro:IPR001164 node/signature, not a gene product - - n/a GO:0005096 (IEA)
InterPro:IPR004148 node/signature, not a gene product - - n/a GO:0005737 (IEA)
InterPro:IPR045258 node/signature, not a gene product - - n/a GO:0005096 (IEA)
MGI:MGI:2153589 Q6NXL5 Q6NXL5_MOUSE (Acap3) Mus musculus 833 yes GO:0005096 (IBA)
PANTHER:PTN001142372 node/signature, not a gene product - - n/a GO:0005096 (IBA), GO:0005886 (IBA), GO:0010008 (IBA), GO:0030036 (IBA)
PomBase:SPBC17G9.08c Q9UUE2 CSX2_SCHPO (csx2) Schizosaccharomyces pombe (strain 972 / ATCC 24843) 870 yes GO:0005886 (IBA)
RGD:1562939 Q5FVC7 ACAP2_RAT (Acap2) Rattus norvegicus 770 yes GO:0010008 (IBA)
SGD:S000002932 Q04412 AGE1_YEAST (AGE1) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 482 yes GO:0005096 (IBA)
UniProtKB-SubCell:SL-0039 UniProt subcellular-location vocabulary term: Cell membrane (Cellular component) - - n/a GO:0005886 (IEA)
UniProtKB-SubCell:SL-0100 UniProt subcellular-location vocabulary term: Endosome membrane (Cellular component) - - n/a GO:0010008 (IEA)
UniProtKB:Q15057 Q15057 ACAP2_HUMAN (ACAP2) Homo sapiens 778 yes GO:0005096 (IBA), GO:0005886 (IBA)
UniProtKB:Q15286 Q15286 RAB35_HUMAN (RAB35) Homo sapiens 201 NO GO:0005515 (IPI)
UniProtKB:Q5FVC7 Q5FVC7 ACAP2_RAT (Acap2) Rattus norvegicus 770 yes GO:0010008 (ISS), GO:0032456 (ISS), GO:1990090 (ISS)
UniProtKB:Q6ZQK5 Q6ZQK5 ACAP2_MOUSE (Acap2) Mus musculus 770 yes GO:0031267 (IEA)
UniProtKB:Q96P50 Q96P50 ACAP3_HUMAN (ACAP3) Homo sapiens 834 yes GO:0005515 (IPI)
WB:WBGene00000565 Q9XXH8 CNT1_CAEEL (cnt-1) Caenorhabditis elegans 826 yes GO:0005886 (IBA), GO:0010008 (IBA)
dictyBase:DDB_G0276395 Q551Q8 Q551Q8_DICDI (-) Dictyostelium discoideum 843 yes GO:0030036 (IBA)
dictyBase:DDB_G0279649 Q54WI0 Q54WI0_DICDI (-) Dictyostelium discoideum 1333 yes GO:0005096 (IBA), GO:0005886 (IBA), GO:0030036 (IBA)
ensembl:ENSMUSP00000154983 Q6ZQK5 ACAP2_MOUSE (Acap2) Mus musculus 770 yes GO:0031267 (IEA)

Ortholog vs paralog

Classification is by gene symbol and by whether the source carries an ArfGAP domain. Sources cited by IPI rows are interaction partners rather than phylogenetic sources, and are labelled as such.

Does each source hold its own evidence for the term it donates?

An IBA/ISS WITH/FROM list is meant to name experimentally annotated family members. For every source with a resolvable UniProt accession, this queries QuickGO for that protein's own annotations to the donated term (descendants included) and reports the evidence codes found. EXPERIMENTAL means at least one of EXP, HDA, HEP, HGI, HMP, HTP, IDA, IEP, IGI, IMP, IPI.

source UniProt donated term source's own evidence experimental?
AGI_LocusCode:AT5G13300 Q5W7F2 GO:0005096 IBAx1, IDAx1, IEAx1 (n=3) yes
AGI_LocusCode:AT5G13300 Q5W7F2 GO:0005886 IBAx1, IDAx1, IEAx1 (n=3) yes
AGI_LocusCode:AT5G61980 Q9FIT8 GO:0005886 IBAx1, IDAx1, IEAx1 (n=3) yes
FB:FBgn0004133 A1Z714 GO:0030036 IBAx1, IMPx1 (n=2) yes
FB:FBgn0004133 E1JGZ4 GO:0030036 IMPx1 (n=1) yes
FB:FBgn0004133 P91678 GO:0030036 (none) (n=0) no
FB:FBgn0004133 Q8MSU1 GO:0030036 (none) (n=0) no
MGI:MGI:2153589 Q6NXL5 GO:0005096 IBAx1, IEAx1, IMPx1 (n=3) yes
PomBase:SPBC17G9.08c Q9UUE2 GO:0005886 IBAx1, IDAx1 (n=2) yes
RGD:1562939 Q5FVC7 GO:0010008 IBAx1, IDAx1, IEAx1 (n=3) yes
SGD:S000002932 Q04412 GO:0005096 IBAx1, IDAx1, IEAx1 (n=3) yes
UniProtKB:Q15057 Q15057 GO:0005096 IBAx1, IDAx1, IEAx1 (n=3) yes
UniProtKB:Q15057 Q15057 GO:0005886 IBAx1, IDAx1, IEAx1 (n=3) yes
UniProtKB:Q15286 Q15286 GO:0005515 IPIx10 (n=10) yes
UniProtKB:Q5FVC7 Q5FVC7 GO:0010008 IBAx1, IDAx1, IEAx1 (n=3) yes
UniProtKB:Q5FVC7 Q5FVC7 GO:0032456 IMPx1 (n=1) yes
UniProtKB:Q5FVC7 Q5FVC7 GO:1990090 IDAx1 (n=1) yes
UniProtKB:Q6ZQK5 Q6ZQK5 GO:0031267 IPIx1 (n=1) yes
UniProtKB:Q96P50 Q96P50 GO:0005515 IPIx2 (n=2) yes
WB:WBGene00000565 Q9XXH8 GO:0005886 EXPx2, IBAx1, IDAx3, IEAx3 (n=9) yes
WB:WBGene00000565 Q9XXH8 GO:0010008 IBAx1, IDAx2, IEAx1 (n=4) yes
dictyBase:DDB_G0276395 Q551Q8 GO:0030036 IBAx1, IGIx1 (n=2) yes
dictyBase:DDB_G0279649 Q54WI0 GO:0005096 IBAx1, IDAx1, IEAx1 (n=3) yes
dictyBase:DDB_G0279649 Q54WI0 GO:0005886 IBAx1, IDAx1 (n=2) yes
dictyBase:DDB_G0279649 Q54WI0 GO:0030036 IBAx1, IGIx1, IMPx1 (n=3) yes
ensembl:ENSMUSP00000154983 Q6ZQK5 GO:0031267 IPIx1 (n=1) yes

Drosophila blow (FB:FBgn0004133) in detail

FlyBase summary: The gene blown fuse is referred to in FlyBase by the symbol Dmel\blow (CG1363, FBgn0004133). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2R:7580488..7587079. Its molecular function is described by: protein binding. It is involved in the biological process described with: myoblast fusion; mesoderm development; actin cytoskeleton organiz

Other members of the same PANTHER subfamily, from the cached interpro/panther/PTHR23180/PTHR23180-entries.csv:

Scope of PANTHER node PTN001142372