IMD3 (YLR432W, P50095) notes

• IMPDH, EC 1.1.1.205 [UniProt:P50095 "Reaction=IMP + NAD(+) + H2O = XMP + NADH + H(+)"]; Km IMP 100 uM [UniProt:P50095 "KM=100 uM for Inosine 5'-phosphate"].
• Not the drug-responsive paralog PMID:11441018.
• Homo- and hetero-tetramers with Imd4 (IPI rows from PCA, Y2H, AP-MS, and heteromer-of-paralogs study PMID:31454312) [UniProt:P50095 "Seems to be able to form heterotetramers composed from more than 1 of the 3 IMPDH gene products (IMD2-4)"].
• protein binding (GO:0005515) rows removed per policy (Imd4 heteromer; Prp22 from RBP interactome screens). identical protein binding kept non-core (homotetramer).
• Plasma membrane HDA (PMID:16622836) likely contamination of a soluble enzyme -> over-annotated.
• mRNP capture PMID:23222640 -> non-core.