Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Electronic Gene Ontology annotations created by ARBA machine learning models
Identification and purification of two distinct complexes containing the five RAD51 paralogs.
Involvement of Rad51C in two distinct protein complexes of Rad51 paralogs in human cells.
Holliday junction binding activity of the human Rad51B protein.
Ring-shaped Rad51 paralog protein complexes bind Holliday junctions and replication forks as visualized by electron microscopy.
hSWS1·SWSAP1 is an evolutionarily conserved complex required for efficient homologous recombination repair.
The RAD51 paralogs ensure cellular protection against mitotic defects and aneuploidy.
Rad51 paralog complexes BCDX2 and CX3 act at different stages in the BRCA1-BRCA2-dependent homologous recombination pathway.
Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair.
A proteome-scale map of the human interactome network.
Discovery of mutations in homologous recombination genes in African-American women with breast cancer.
A reference map of the human binary protein interactome.
Sequential role of RAD51 paralog complexes in replication fork remodeling and restart.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
A protein interaction landscape of breast cancer.
Structure and function of the RAD51B-RAD51C-RAD51D-XRCC2 tumour suppressor.
Multimodal cell maps as a foundation for structural and functional genomics.
Identification of a novel human RAD51 homolog, RAD51B.
Isolation and characterization of RAD51C, a new human member of the RAD51 family of related genes.
Isolation of novel human and mouse genes of the recA/RAD51 recombination-repair gene family.
BCDX2 complex stabilizes RAD51 filament
CX3 complex binds D-loop structures
BLM mediates dissolution of double Holliday junction
MUS81:EME1,EME2 cleaves D-loop
Resolution of D-loops cleaved by MUS81:EME1 or MUS81:EME2
Resolution of Holliday junctions cleaved by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2)
Ligation of DNA and formation of Holliday structures following repair synthesis
Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2)
D-loop dissociation and strand annealing
D-loop extension by DNA polymerases
D-loop formation mediated by PALB2, BRCA2 and RAD51
Defective D-loop formation mediated by PALB2, BRCA2 and RAD51 due to loss-of-function of BRCA1 in PALB2 binding
Defective D-loop formation mediated by PALB2, BRCA2 and RAD51 due to loss-of-function of PALB2 in BRCA1 binding
Defective D-loop formation mediated by PALB2, BRCA2 and RAD51 due to loss-of-function of PALB2 in binding to BRCA2/RAD51/RAD51C
Defective recruitment of BRCA2 and RAD51 due to loss of BRCA2 function in PALB2 binding
RAD51B:RAD51C binds single-stranded DNA
Mediator function of the human Rad51B-Rad51C complex in Rad51/RPA-catalyzed DNA strand exchange.
Structural insights into BCDX2 complex function in homologous recombination.
RAD51 paralogs synergize with RAD51 to protect reversed forks from cellular nucleases.
Cryo-electron microscopic visualization of RAD51 filament assembly and end-capping by XRCC3-RAD51C-RAD51D-XRCC2.
Distinct functions of mammalian RAD51 paralogs in genome maintenance.
Differential Requirements for the RAD51 Paralogs in Genome Repair and Maintenance in Human Cells.
Disruption of muREC2/RAD51L1 in mice results in early embryonic lethality which can Be partially rescued in a p53(-/-) background.