Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Combined Automated Annotation using Multiple IEA Methods
TMEM120A and B: Nuclear Envelope Transmembrane Proteins Important for Adipocyte Differentiation.
TACAN Is an Ion Channel Involved in Sensing Mechanical Pain.
A reference map of the human binary protein interactome.
Involvement of TACAN, a Mechanotransducing Ion Channel, in Inflammatory But Not Neuropathic Hyperalgesia in the Rat.
Analysis of the mechanosensor channel functionality of TACAN.
TMEM120A is a coenzyme A-binding membrane protein with structural similarities to ELOVL fatty acid elongase.
TMEM120A contains a specific coenzyme A-binding site and might not mediate poking- or stretch-induced channel activities in cells.
Cryo-EM structures of human TMEM120A and TMEM120B.
Gain-of-function genetic screening identifies the antiviral function of TMEM120A via STING activation.
Genomic loci mispositioning in Tmem120a knockout mice yields latent lipodystrophy.
TMEM120A/TACAN inhibits mechanically activated PIEZO2 channels.
Regulation of PKD2 channel function by TACAN.
Phosphatidic acid is an endogenous negative regulator of PIEZO2 channels and mechanical sensitivity.
TMEM120A maintains adipose tissue lipid homeostasis through ER CoA channeling.
From nociception to therapy: The expanding role of TMEM proteins in pain.
A conserved ER protein prevents lipotoxicity by stimulating the key enzyme in glycerolipid synthesis.
Biolayer Interferometry for Investigating Membrane Protein-Inhibitor Binding: TACAN Mutant and GsMTx4 As a Model System.