Q9W255 is native qkr58E-1-PA, 396 residues. UniProt documents KH domain 111–209 and FlyBase lists distinct shorter PC/PD products. The exact accession retains the RNA-binding domain.
PMID:18981222(https://pubmed.ncbi.nlm.nih.gov/18981222/) reports affinity-purified fly spliceosomal B and C complexes and mass spectrometry. FlyBase specifically assigns qkr58E-1 to these complexes; the cached abstract describes the experiment but does not reproduce the gene table. Those curated experimental assignments are retained, not rejected because the abstract omits a protein name. PMID:25294944(https://pubmed.ncbi.nlm.nih.gov/25294944/) full text is cached and describes blinded protein-trap localization followed by gene assignment; the target-specific nuclear row is available through GOA.
Broad RNA binding and regulation of gene expression are supported, with more precise existing terms available. The fungal BBP paragraph overreaches the available evidence in claiming necessity and exact branch-site/tract/3′-site recognition: those individual claims remain UNC. No target-specific binding motif is inferred from the generic KH fold.
The primary PMC spliceosome table was additionally checked through its indexed table text: “KHDRBS2 | gi|24658086 | CG3613 | QKR58E-1”. This independently identifies the target in the experimental protein list. The directly opened PMC endpoint presents a browser challenge, so this is an inspected indexed table excerpt, not a claim that the local abstract cache contains the full table.
The completed Falcon synthesis identified direct RNP-network and selected-splice-event evidence. The full cached PMID:26294687 was read: QKR58E-1 coassociates with specific RNAs and spliceosome-related proteins, with reciprocal RNA-binding relationships involving SYP and QKR54B. The assay recovers complexes without crosslinking, so it does not prove direct contact for every RNA. PMID:27919077 is abstract-only in the publication cache; the publisher HTML and extracted Extended Data text are retained locally. Extended Data Figure 10b explicitly lists Qkr58E-1 knockdown among perturbations affecting fl(2)d splicing; panels g/h describe YT521-B interaction with and without RNase. This supports selected splicing regulation without assigning methylation-reader or writer activity. The report’s statement that direct localization was not found is incomplete: the original curated HDA nuclear annotation from PMID:25294944 is retained. The exact fungal branch-site motif remains unestablished.