Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

A reference map of the human binary protein interactome.

A peptide encoded by a transcript annotated as long noncoding RNA enhances SERCA activity in muscle.

The transmembrane peptide DWORF activates SERCA2a via dual mechanisms.

Dwarf open reading frame (DWORF) is a direct activator of the sarcoplasmic reticulum calcium pump SERCA.

Micropeptide hetero-oligomerization adds complexity to the calcium pump regulatory network.

Inhibitory and stimulatory micropeptides preferentially bind to different conformations of the cardiac calcium pump.

Newly Discovered Micropeptide Regulators of SERCA Form Oligomers but Bind to the Pump as Monomers.

Phosphorylation of phospholamban promotes SERCA2a activation by dwarf open reading frame (DWORF).

Structural Elements of Dwarf Open Reading Frame Required for Activation of the Sarco-Endoplasmic Reticulum Calcium Pump.

The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy.

Interaction of DWORF with SERCA and PLB as determined by EPR spectroscopy.

A kink in DWORF helical structure controls the activation of the sarcoplasmic reticulum Ca(2+)-ATPase.

Early vertebrate origin and diversification of small transmembrane regulators of cellular ion transport.