Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
BAG-2 acts as an inhibitor of the chaperone-associated ubiquitin ligase CHIP.
Identification of intracellular proteins associated with the EBV-encoded nuclear antigen 5 using an efficient TAP procedure and FT-ICR mass spectrometry.
The cochaperone BAG2 sweeps paired helical filament- insoluble tau from the microtubule.
Dynamic protein-protein interaction wiring of the human spliceosome.
Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.
Binding of human nucleotide exchange factors to heat shock protein 70 (Hsp70) generates functionally distinct complexes in vitro.
The BAG2 protein stabilises PINK1 by decreasing its ubiquitination.
Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease.
Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation.
The BAG2 and BAG5 proteins inhibit the ubiquitination of pathogenic ataxin3-80Q.
A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.
A proteome-scale map of the human interactome network.
Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.
Quantitative interaction proteomics of neurodegenerative disease proteins.
A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Roles of tau protein in health and disease.
Comparative Protein Interaction Network Analysis Identifies Shared and Distinct Functions for the Human ROCO Proteins.
An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei.
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS(G13D).
A reference map of the human binary protein interactome.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
With or without You: Co-Chaperones Mediate Health and Disease by Modifying Chaperone Function and Protein Triage.
DNAJB1-PRKACA in HEK293T cells induces LINC00473 overexpression that depends on PKA signaling.
The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Interactome dynamics of RAF1-BRAF kinase monomers and dimers.
BAG2, MAD2L1, and MDK are cancer-driver genes and candidate targets for novel therapies in malignant pleural mesothelioma.
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BAG2 is identified as a candidate cancer-driver gene and diagnostic-adjunct biomarker in malignant pleural mesothelioma, being significantly upregulated in tumor RNA-seq and showing moderate-to-strong immunohistochemical expression in mesothelioma but not in reactive mesothelium; this is a disease-association rather than a new molecular function for BAG2.
Multimodal cell maps as a foundation for structural and functional genomics.
Control of glycogen synthesis in cultured human muscle cells.
An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators.
HSP110s exchange ATP for ADP on HSP70s:ADP
BAG2 UniProtKB record (O95816)
Manual BAG2 curation notes