Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniPathway vocabulary mapping
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Expression, purification, and characterization of natural mutants of human aldolase B. Role of quaternary structure in catalysis.
Functional and molecular modelling studies of two hereditary fructose intolerance-causing mutations at arginine 303 in human liver aldolase.
Molecular analysis of the aldolase B gene in patients with hereditary fructose intolerance from Spain.
Physical interaction between aldolase and vacuolar H+-ATPase is essential for the assembly and activity of the proton pump.
Novel interaction partners of Bardet-Biedl syndrome proteins.
Hereditary fructose intolerance: functional study of two novel ALDOB natural variants and characterization of a partial gene deletion.
Toward an understanding of the protein interaction network of the human liver.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
Construction and expression of human aldolase A and B expression plasmids in Escherichia coli host.
Catalytic deficiency of human aldolase B in hereditary fructose intolerance caused by a common missense mutation.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Aldolase B suppresses hepatocellular carcinogenesis by inhibiting G6PD and pentose phosphate pathways.
Human skeletal-muscle aldolase: N-terminal sequence analysis of CNBr- and o-iodosobenzoic acid-cleavage fragments.
Mode of interactions of human aldolase isozymes with cytoskeletons.
Defective ALDOB does not cleave Fru 1-P to GA and DHAP
ALDOB tetramer cleaves Fru-1-P to GA and DHAP
Aldolase tetramers convert GA3P and DHAP to F1,6PP
Aldolase tetramer cleaves F1,6PP
Aldolase-B knockout in mice phenocopies hereditary fructose intolerance in humans.
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Targeted mouse Aldob deficiency reproduces fructose-sensitive pathology relevant to the donor phenotype evidence.
"The Aldo2(-/-) homozygous mice show similar pathology following exposure to fructose as humans with HFI"
Ketohexokinase C blockade ameliorates fructose-induced metabolic dysfunction in fructose-sensitive mice.
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Blocking the upstream KHK step prevents disease-model hypoglycemia and injury; this supports pathway context rather than a different ALDOB reaction.
"the absence or inhibition of ketohexokinase (Khk), an enzyme upstream of aldolase B, is sufficient to prevent hypoglycemia"
The conversion of (4- 3 H)fructose and of (4- 3 H)glucose to liver glycogen in the mouse. An investigation of the glyceraldehyde crossroads.
Author Correction: Aldolase B suppresses hepatocellular carcinogenesis by inhibiting G6PD and pentose phosphate pathways.
Toward an understanding of the protein interaction network of the human liver.
UniProtKB P05062 human ALDOB record
ALDOB source-access notes with attributed public-article excerpts