Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Combined Automated Annotation using Multiple IEA Methods
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Multimodal cell maps as a foundation for structural and functional genomics.
P4HA2 activates mTOR via hydroxylation and targeting P4HA2-mTOR inhibits lung adenocarcinoma cell growth.
P4HA2 hydroxylates SUFU to regulate the paracrine Hedgehog signaling and promote B-cell lymphoma progression.
P4HA2 promotes tumor progression and is transcriptionally regulated by SP1 in colorectal cancer.
Enhanced Collagen Prolyl 4-Hydroxylase Activity and Expression Promote Cancer Progression via Both Canonical and Non-Canonical Mechanisms.
Prolyl and lysyl hydroxylases in collagen synthesis.
Cloning of the human prolyl 4-hydroxylase alpha subunit isoform alpha(II) and characterization of the type II enzyme tetramer. The alpha(I) and alpha(II) subunits do not form a mixed alpha(I)alpha(II)beta2 tetramer.
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The human type II prolyl 4-hydroxylase is an (alpha-II)2-beta2 tetramer with P4HB/PDI as the beta subunit and catalyzes formation of 4-hydroxyproline in collagens (EC 1.14.11.2).
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The alpha(I) and alpha(II) subunits do not co-assemble into a mixed alpha(I)alpha(II)beta2 tetramer; the type II enzyme is kinetically similar to type I except for a much higher Ki for poly(L-proline).
Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines
Proline hydroxylases hydroxylate Polyprotein
UniProt entry O15460 (P4HA2_HUMAN), Prolyl 4-hydroxylase subunit alpha-2