Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Combined Automated Annotation using Multiple IEA Methods
UniProtKB entry P23526 (SAHH_HUMAN), Adenosylhomocysteinase
Substrate binding stabilizes S-adenosylhomocysteine hydrolase in a closed conformation.
Large-scale proteomics and phosphoproteomics of urinary exosomes.
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
A proteome-scale map of the human interactome network.
Widespread macromolecular interaction perturbations in human genetic disorders.
Sequence of full length cDNA for human S-adenosylhomocysteine hydrolase.
Architecture of the human interactome defines protein communities and disease networks.
Mutations in S-adenosylhomocysteine hydrolase (AHCY) affect its nucleocytoplasmic distribution and capability to interact with S-adenosylhomocysteine hydrolase-like 1 protein.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
A reference map of the human binary protein interactome.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
AHCY:NAD+ tetramer hydrolyses AdoHcy
Defective AHCY does not hydrolyse AdoHcy
Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.
S-adenosyl-l-homocysteine hydrolase links methionine metabolism to the circadian clock and chromatin remodeling.
The AHCY-adenosine complex rewires mRNA methylation to enhance fatty acid biosynthesis and tumorigenesis.
Catalytic strategy of S-adenosyl-L-homocysteine hydrolase: transition-state stabilization and the avoidance of abortive reactions.
S-adenosylhomocysteine hydrolase deficiency in a human: a genetic disorder of methionine metabolism.
S-adenosylhomocysteine hydrolase (AHCY) deficiency: two novel mutations with lethal outcome.