Use of the ND evidence code for Gene Ontology (GO) terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Uncharacterized WD repeat-containing protein C17D11.08 (dca7, SPBC17D11.08), Schizosaccharomyces pombe
ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
Phosphoproteome analysis of fission yeast.
A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human.
The adaptor protein DCAF7 mediates the interaction of the adenovirus E1A oncoprotein with the protein kinases DYRK1A and HIPK2.
Deep research report: dca7 (SPBC17D11.08) as a DCAF7-like WD40 protein
OpenScientist report on the conserved Dca7 kinase-scaffold hypothesis
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The focused report supports the conserved DCAF7/Yak-kinase scaffold hypothesis, while retaining the caveat that a high-throughput Dca7-Ppk15 interaction is not yet proof of a native S. pombe scaffold function.
"Dca7 = DCAF7/WDR68 ortholog; Dca7 binds ppk15 (Yak/DYRK ortholog) in pombe; the human orthologous pair binds directly and the interaction is conserved."
OpenScientist report on the Dca7 Cul4-Ddb1 substrate-receptor hypothesis
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The focused report independently supports treating the Cul4-RING E3 complex annotation as an over-strong orthology transfer rather than a demonstrated fission-yeast complex membership.
"no recorded interaction with any pombe CRL4 subunit"