Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Involvement of a triton-insoluble floating fraction in Dictyostelium cell-cell adhesion.
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gp80 is a phospholipid-anchored cell adhesion molecule that partitions into a sterol-rich, Triton-insoluble floating fraction and colocalizes with F-actin at cell-cell contacts.
"gp80 colocalized with F-actin, porin, and comitin at cell-cell contacts"
Overexpression of the csA cell adhesion molecule under its own cAMP-regulated promoter impairs morphogenesis in Dictyostelium.
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Strong overexpression of csA delays aggregation and alters morphogenesis.
"When the csA protein was strongly overexpressed under the developmental control of the csA promoter, morphogenesis was substantially altered"
Comparison of molecular mechanisms mediating cell contact phenomena in model developmental systems: an exploration of universality.
Selective elimination of the contact site A protein of Dictyostelium discoideum by gene disruption.
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Gene disruption of csA drastically reduces EDTA-stable (Ca2+-independent) adhesion, confirming csA acts as a cell-adhesion molecule.
"EDTA-stable adhesion was drastically reduced as compared to wild type, confirming that the contact site A glycoprotein acts as a cell-adhesion molecule"
Response of Dictyostelium discoideum to UV-C and involvement of poly (ADP-ribose) polymerase.
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csA expression is markedly reduced following UV-C irradiation, as a developmental readout rather than an effector of the UV-C response.
"expression of csA and ctnA was markedly reduced"
Leaps and lulls in the developmental transcriptome of Dictyostelium discoideum.
Curcumin inhibits development and cell adhesion in Dictyostelium discoideum: Implications for YakA signaling and GST enzyme function.
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Curcumin suppresses expression of cell adhesion proteins including csA, delaying adhesion and development.
"expression of the extracellular matrix/cell adhesion proteins (DdCAD and csA)"
The contact site A glycoprotein mediates cell-cell adhesion by homophilic binding in Dictyostelium discoideum.
Filopodia are enriched in a cell cohesion molecule of Mr 80,000 and participate in cell-cell contact formation in Dictyostelium discoideum.
Inhibition of cell-cell binding at the aggregation stage of Dictyostelium discoideum development by monoclonal antibodies directed against an 80,000-dalton surface glycoprotein.
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Anti-gp80 monoclonal antibodies block EDTA-resistant contacts and inhibit reassociation, indicating a direct role of gp80 in cell-cell binding.
"consistent with a direct role of gp80 in cell-cell binding"
Monoclonal antibody recognizing gp80, a membrane glycoprotein implicated in intercellular adhesion of Dictyostelium discoideum.
Oriented binding of a lipid-anchored cell adhesion protein onto a biosensor surface using hydrophobic immobilization and photoactive crosslinking.
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Immobilized csA interacts with csA in solution, demonstrating homophilic (identical protein) binding.
"Interaction of the immobilized csA protein with csA in solution established that the bound molecules are capable of taking part in homophilic interactions"
Novel redistribution of the Ca(2+)-dependent cell adhesion molecule DdCAD-1 during development of Dictyostelium discoideum.
Detection of subtle phenotypes: the case of the cell adhesion molecule csA in Dictyostelium.
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Under semi-natural conditions csA is required for efficient development and confers a selective advantage; csA-null cells show reduced adhesion and motility.
"evidence is provided that csA is required for development"