Gene Ontology annotation through association of InterPro records with GO terms.
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt.
Combined Automated Annotation using Multiple IEA Methods.
The stem cell population of Arabidopsis shoot meristems in maintained by a regulatory loop between the CLAVATA and WUSCHEL genes.
Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
CORONA, a member of the class III homeodomain leucine zipper gene family in Arabidopsis, regulates stem cell specification and organogenesis.
Analysis of the transcription factor WUSCHEL and its functional homologue in Antirrhinum reveals a potential mechanism for their roles in meristem maintenance.
WUSCHEL regulates cell differentiation during anther development.
Altered expression of the bZIP transcription factor DRINK ME affects growth and reproductive development in Arabidopsis thaliana.
A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration.
CrY2H-seq: a massively multiplexed assay for deep-coverage interactome mapping.
A PXY-Mediated Transcriptional Network Integrates Signaling Mechanisms to Control Vascular Development in Arabidopsis.
The protein-protein interaction landscape of transcription factors during gynoecium development in Arabidopsis.
The WUSCHEL gene is required for shoot and floral meristem integrity in Arabidopsis.
Role of WUSCHEL in regulating stem cell fate in the Arabidopsis shoot meristem.
Deep research on WUS function
Falcon (Edison Scientific) deep research on Arabidopsis WUSCHEL (WUS) function
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"**Core molecular role:** WUS functions as a transcription factor that **maintains stem-cell identity** and positions/controls the stem-cell niche by regulating gene expression in a non-cell-autonomous manner."
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"WUS was described early as a **nuclear-localized homeodomain protein**, consistent with transcription factor function."
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"A central experimentally supported output of WUS is activation of **CLV3**, which then signals back to restrict WUS."
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"a Dex-inducible WUS system showed **CLV3 transcript induction within 4 hours**, and critically the induction occurred **even in the presence of cycloheximide**, supporting a direct transcriptional effect"
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"WUS protein is **mobile**, forming a gradient from the OC/rib meristem into adjacent/apical cells"
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"A functional **pWUS::eGFP-WUS** fusion rescued the mutant phenotype, and adding an **NLS** inhibited movement. WUS protein was reported to move laterally by **at least two cell layers**."
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"movement is **plasmodesmata-dependent** and functionally important"
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"**WUS–STM interaction:** WUS physically interacts with **SHOOT MERISTEMLESS (STM)** (pull-down, yeast two-hybrid, BiFC, co-IP)."
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"**DA1 physically interacts with WUS and cleaves it**, leading to destabilization."