Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Combined Automated Annotation using Multiple IEA Methods
Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein.
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Der p 2 has structural and functional homology with MD-2 and reconstitutes LPS-driven TLR4 signalling in the absence of MD-2, acting as an auto-adjuvant.
"reconstituting LPS-driven TLR4 signalling in the absence of MD-2."
UniProt entry P49278 (Mite group 2 allergen Der p 2), Dermatophagoides pteronyssinus