fluG (Aspergillus nidulans) — curation notes
UniProt P38094 (FLUG_EMENI). GSI-related cytoplasmic protein; upstream-most
activator of conidiation. Upstream-activation tier of the
conidiation_regulatory_cascade module.
- Required for the extracellular developmental signal; fluG-null = fluffy/aconidial.
PMID:7926755.
- UniProt: "May function as a GSI-related enzyme in synthesizing a small" signal —
i.e. classical glutamine synthetase activity is putative, not demonstrated
(A. nidulans glutamine synthesis is via GlnA). GO:0004356 / GO:1901704 kept
non-core with this caveat; no MF asserted in core_functions.
- GO:0016787 hydrolase activity (IEA) flagged over-annotation (FluG is a GS-family
ligase, not a hydrolase). GO:0045461 ST biosynthetic process flagged
over-annotation (regulator → GO:0010914).