Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Cloning and analysis of human Apg16L.
Network organization of the human autophagy system.
Structure of the human ATG12~ATG5 conjugate required for LC3 lipidation in autophagy.
Interaction between FIP200 and ATG16L1 distinguishes ULK1 complex-dependent and -independent autophagy.
TMEM59 defines a novel ATG16L1-binding motif that promotes local activation of LC3.
FIP200 regulates targeting of Atg16L1 to the isolation membrane.
Structural basis of ATG3 recognition by the autophagic ubiquitin-like protein ATG12.
IRGM governs the core autophagy machinery to conduct antimicrobial defense.
TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity.
WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy.
The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation.
The WD40 domain of ATG16L1 is required for its non-canonical role in lipidation of LC3 at single membranes.
Distinct functions of ATG16L1 isoforms in membrane binding and LC3B lipidation in autophagy-related processes.
A reference map of the human binary protein interactome.
RAB33B recruits the ATG16L1 complex to the phagophore via a noncanonical RAB binding protein.
SPATA33 is an autophagy mediator for cargo selectivity in germline mitophagy.
Non-canonical autophagy functions of ATG16L1 in epithelial cells limit lethal infection by influenza A virus.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
ER-phagy restrains inflammatory responses through its receptor UBAC2.
Multimodal cell maps as a foundation for structural and functional genomics.
ATG16L1 complex transfers LC3 from ATG3 to PE
WIPI2 binds ATG12:ATG5:ATG16L