Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica
Establishes the complete genome sequence of Bordetella pertussis strain Tohama I, including locus BP0922 encoding this PrpF-family protein.
file:BORPE/Q7VZI5/Q7VZI5-uniprot.txt
UniProt entry Q7VZI5
Classifies Q7VZI5 as a 3-methylitaconate isomerase belonging to the PrpF family, with isomerase activity (GO:0016853) assigned by IEA from the UniProtKB-KW pipeline.
Records PrpF-like domain (IPR007400), PrpF Pfam domain (PF04303), and diaminopimelate epimerase-like fold assignment.
file:BORPE/Q7VZI5/Q7VZI5-deep-research-falcon.md
Deep research summary for Q7VZI5
Identifies Q7VZI5/BP0922 as a cytoplasmic PrpF-family 3-methylitaconate isomerase participating in propionate utilization via the 2-methylcitric acid cycle.
Notes that functional assignment is high-confidence homology-based prediction rather than direct B. pertussis-specific experimentation.
Predicts cytoplasmic localization based on the soluble nature of PrpF-family metabolic enzymes and absence of secretion or membrane-anchoring signals.