TreeGrafter-generated GO annotations
Combined Automated Annotation using Multiple IEA Methods
UniProt entry TRPB_PSEPK (Q88RP6)
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TrpB synthesizes L-tryptophan from indole and L-serine; PLP cofactor; pathway L-tryptophan from chorismate step 5/5; functions as a tetramer of two alpha and two beta chains.
"FUNCTION: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. SUBUNIT: Tetramer of two alpha and two beta chains."
Functional analysis of aromatic biosynthetic pathways in Pseudomonas putida KT2440
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In P. putida KT2440 there is a single pathway from chorismate to tryptophan; the trp genes are in unlinked regions with trpBA organized as an operon, and auxotroph screening shows the pathway is required for de novo tryptophan biosynthesis.
"Genes for tryptophan biosynthesis are grouped in unlinked regions with the trpBA and trpGDE genes organized as operons... There is a single pathway from chorismate leading to the biosynthesis of tryptophan."