DFG10 (P40526) notes

Module: dolichol_phosphate_sugar_donor_supply, role = polyprenal reductase (SRD5A3). No YeastCyc reaction.

Evidence journal

• Polyprenal, not polyprenol, reductase PMID:38821050
• dfg10 lipid phenotype PMID:38821050
• Ortholog of SRD5A3, glycosylation defect PMID:20637498
• Non-steroid substrate PMID:20637498

Annotation decisions

• ISS 3-oxo-5-alpha-steroid 4-dehydrogenase: MODIFY to GO:0160198 polyprenal reductase.
• Dolichol-linked oligosaccharide biosynthesis (IBA, IMP): KEEP_AS_NON_CORE (upstream supplier of the carrier).
• Lipid metabolic process / CH-CH oxidoreductase IEA: MODIFY to specific terms. Pseudohyphal growth IMP: KEEP_AS_NON_CORE.