ILV5 (YLR355C, P06168) notes

• Ketol-acid reductoisomerase EC 1.1.1.86, mitochondrial [UniProt:P06168 "RecName: Full=Ketol-acid reductoisomerase, mitochondrial"]; gene identity PMID:3027658.
• Mitochondrial; cytosolic only after N-terminal truncation PMID:18193418 (of the Delta46 construct); native pathway PMID:18193418.
• mtDNA moonlighting:
• PMID:7621838
• PMID:7621838
• PMID:18023287
• PMID:18826960
• Nucleoid crosslinking PMID:10869431 (abstract does not name Ilv5; full text not cached).

Curation observations

• 3 RCA cytosol rows -> REMOVE.
• GO:1901859 "negative regulation of mitochondrial DNA metabolic process" (3 rows) appears to be the post-obsoletion replacement of GO:0000002 mitochondrial genome maintenance; semantically awkward, kept as non-core and raised as a suggested question.
• Two core functions: KARI (BCAA biosynthesis) and dsDNA binding in nucleoid (mtDNA maintenance).