KGD1 (YIL125W, P20967) notes
- E1 (KE1) of the 2-oxoglutarate dehydrogenase complex PMID:2072900.
- Reaction: lipoyl-lysine + 2-oxoglutarate -> S-succinyldihydrolipoyl-lysine + CO2, TPP cofactor [UniProt:P20967].
- Assembly: KE1 binds the KE2-E3 particle PMID:2072900; Kgd4 binds the Kgd1-Kgd2 core and recruits Lpd1 PMID:25165143.
- Mitochondrial matrix; part of KGDC associates with nucleoids PMID:11926067.
- GO note: the overall NAD+ KGDH term (GO:0034602) is obsolete; GO:0004591 serves for the complex reaction, so RCA contributes_to rows on E2 are acceptable.