Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
YeastPathways to GO-CAM conversion
Protein sorting in the late Golgi of Saccharomyces cerevisiae does not require mannosylated sphingolipids.
SKN1, a novel plant defensin-sensitivity gene in Saccharomyces cerevisiae, is implicated in sphingolipid biosynthesis.
Skn1 and Ipt1 negatively regulate autophagy in Saccharomyces cerevisiae.
Biosynthesis of phosphoinositol-containing sphingolipids from phosphatidylinositol by a membrane preparation from Saccharomyces cerevisiae.
Synthesis of mannose-(inositol-P)2-ceramide, the major sphingolipid in Saccharomyces cerevisiae, requires the IPT1 (YDR072c) gene.
Syringomycin E inhibition of Saccharomyces cerevisiae: requirement for biosynthesis of sphingolipids with very-long-chain fatty acids and mannose- and phosphoinositol-containing head groups.
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ipt1 (syr4) deletion strains lack M(IP)2C and are resistant to syringomycin E.
"Deletion Deltasyr4/ipt1 strains were viable, were resistant to syringomycin E, did not produce mannosyl-diinositolphosphoryl-ceramide"
IPT1-independent sphingolipid biosynthesis and yeast inhibition by syringomycin E and plant defensin DmAMP1.
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The terminal sphingolipid M(IP)2C, rather than IPT1 itself, is required for syringomycin E and DmAMP1 action.
"These results show that the terminal sphingolipid but not IPT1 expression is required for fungicidal activity"
Mannosyl-diinositolphospho-ceramide, the major yeast plasma membrane sphingolipid, governs toxicity of Kluyveromyces lactis zymocin.
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KTI6 is allelic to IPT1; kti6/ipt1 cells lack M(IP)2C, resist zymocin and do not import its gamma subunit.
"KTI6 is allelic to IPT1, coding for mannosyl-diinositolphospho-ceramide [M(IP)(2)C] synthase"
A gene encoding a sphingolipid biosynthesis enzyme determines the sensitivity of Saccharomyces cerevisiae to an antifungal plant defensin from dahlia (Dahlia merckii).
SGD gene description for IPT1 (yeast)