GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:14630798
Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions.
PMID:23704930
APOOL is a cardiolipin-binding constituent of the Mitofilin/MINOS protein complex determining cristae morphology in mammalian mitochondria.
PMID:25764979
The non-glycosylated isoform of MIC26 is a constituent of the mammalian MICOS complex and promotes formation of crista junctions.
PMID:25781180
Detailed analysis of the human mitochondrial contact site complex indicate a hierarchy of subunits.
PMID:25918844
MICOS coordinates with respiratory complexes and lipids to establish mitochondrial inner membrane architecture.
PMID:25997101
QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology.
PMID:26477565
Evolution and structural organization of the mitochondrial contact site (MICOS) complex and the mitochondrial intermembrane space bridging (MIB) complex.
PMID:26968360
Distinct Roles of Mic12 and Mic27 in the Mitochondrial Contact Site and Cristae Organizing System.
PMID:27479602
Mic13 Is Essential for Formation of Crista Junctions in Mammalian Cells.
PMID:28845423
Cristae architecture is determined by an interplay of the MICOS complex and the F(1)F(O) ATP synthase via Mic27 and Mic10.
PMID:29733859
Assembly of the Mitochondrial Cristae Organizer Mic10 Is Regulated by Mic26-Mic27 Antagonism and Cardiolipin.
PMID:32788226
MIC26 and MIC27 cooperate to regulate cardiolipin levels and the landscape of OXPHOS complexes.
PMID:33268479
Drosophila MICOS knockdown impairs mitochondrial structure and function and promotes mitophagy in muscle tissue.
PMID:34800366
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.
PMID:37279200
MIC26 and MIC27 are bona fide subunits of the MICOS complex in mitochondria and do not exist as glycosylated apolipoproteins.
PMID:42647630
The molecular basis of mitochondrial crista formation by the MIC10 complex.
Reactome:R-HSA-481007
Exocytosis of platelet alpha granule contents
file:human/APOOL/APOOL-uniprot.txt
UniProtKB entry Q6UXV4 (MIC27_HUMAN), entry version 154, 02-SEP-2026
file:human/APOOL/APOOL-bioinformatics/RESULTS.md
APOOL bioinformatics, inter-transmembrane loop conservation across PTHR14564
file:human/APOOL/APOOL-deep-research-affinage.md
Affinage mechanistic annotation for APOOL (human)