Electronic Gene Ontology annotations created by transferring manual GO annotations between orthologous microbial proteins.
An inosine triphosphate pyrophosphatase safeguards plant nucleic acids from aberrant purine nucleotides
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Arabidopsis ITPA dephosphorylates deaminated nucleoside di- and triphosphates to the respective monophosphates
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ITPA loss-of-function causes inosine di- and triphosphate accumulation in vivo and an elevated inosine and deoxyinosine content in RNA and DNA
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Inosine triphosphate pyrophosphatase is part of a molecular protection system in plants, preventing the accumulation of (d)ITP and its usage for nucleic acid synthesis
Research notes on NCGR_LOCUS3088 ITPase
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HAM1/ITPase family is well-characterized across bacteria, yeast, plants, and mammals
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All annotations are IEA via HAMAP rule MF_03148 or UniProtKB keywords