GO annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified annotations to orthologs by curator judgment
Annotation inferences using phylogenetic trees
GO annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping
GO annotation based on curation of immunofluorescence data (HPA)
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Automatic assignment of GO terms using logical inference, based on inter-ontology links
Automatic GO annotation from UniProtKB-KW mapping
Combined Automated Annotation using Multiple IEA Methods
Integrin-linked kinase regulates phosphorylation of serine 473 of protein kinase B by an indirect mechanism.
A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading.
Modulation of integrin signal transduction by ILKAP, a protein phosphatase 2C associating with the integrin-linked kinase, ILK1.
A novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate interaction.
Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites.
Actopaxin interacts with TESK1 to regulate cell spreading on fibronectin.
Towards a proteome-scale map of the human protein-protein interaction network.
Integrin-linked kinase interacts with caspase-9 and -8 in an adhesion-dependent manner for promoting radiation-induced apoptosis in human leukemia cells.
Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH).
Phosphorylation-dependent regulation of nuclear localization and functions of integrin-linked kinase.
Interaction of integrin-linked kinase with the kidney chloride/bicarbonate exchanger, kAE1.
Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization.
Rictor and integrin-linked kinase interact and regulate Akt phosphorylation and cancer cell survival.
The structural basis of integrin-linked kinase-PINCH interactions.
EphA1 interacts with integrin-linked kinase and regulates cell morphology and motility.
Defining the membrane proteome of NK cells.
The pseudoactive site of ILK is essential for its binding to alpha-Parvin and localization to focal adhesions.
Type I collagen promotes epithelial-mesenchymal transition through ILK-dependent activation of NF-kappaB and LEF-1.
CYR61 regulates BMP-2-dependent osteoblast differentiation through the {alpha}v{beta}3 integrin/integrin-linked kinase/ERK pathway.
The roles of two distinct regions of PINCH-1 in the regulation of cell attachment and spreading.
Thymosin beta4 inhibits TNF-alpha-induced NF-kappaB activation, IL-8 expression, and the sensitizing effects by its partners PINCH-1 and ILK.
Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.
Next-generation sequencing to generate interactome datasets.
Biochemical, proteomic, structural, and thermodynamic characterizations of integrin-linked kinase (ILK): cross-validation of the pseudokinase.
Phosphorylation and interaction of myopodin by integrin-link kinase lead to suppression of cell growth and motility in prostate cancer cells.
Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.
Platelet proteome analysis reveals integrin-dependent aggregation defects in patients with myelodysplastic syndromes.
A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.
Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.
Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signalling.
A proteome-scale map of the human interactome network.
A massively parallel pipeline to clone DNA variants and examine molecular phenotypes of human disease mutations.
Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.
A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways.
Architecture of the human interactome defines protein communities and disease networks.
Kindlin-2 interacts with a highly conserved surface of ILK to regulate focal adhesion localization and cell spreading.
Non-catalytic signaling by pseudokinase ILK for regulating cell adhesion.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
A reference map of the human binary protein interactome.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Integrin-linked kinase (ILK): the known vs. the unknown and perspectives.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
A central chaperone-like role for 14-3-3 proteins in human cells.
Multimodal cell maps as a foundation for structural and functional genomics.
Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase.
Identification and characterization of a mouse protein kinase that is highly homologous to human integrin-linked kinase.