Gene Ontology annotation through association of InterPro records with GO terms

Electronic Gene Ontology annotations created by ARBA machine learning models

HAC-1, a Drosophila homolog of APAF-1 and CED-4 functions in developmental and radiation-induced apoptosis.

An essential role for the caspase dronc in developmentally programmed cell death in Drosophila.

Multiple apoptotic caspase cascades are required in nonapoptotic roles for Drosophila spermatid individualization.

Drosophila caspase transduces Shaggy/GSK-3beta kinase activity in neural precursor development.

The two Drosophila cytochrome C proteins can function in both respiration and caspase activation.

Systematic in vivo RNAi analysis of putative components of the Drosophila cell death machinery.

The Drosophila melanogaster Apaf-1 homologue ARK is required for most, but not all, programmed cell death.

Autophagy occurs upstream or parallel to the apoptosome during histolytic cell death.

ARK, the Apaf-1 related killer in Drosophila, requires diverse domains for its apoptotic activity.

Local caspase activity directs engulfment of dendrites during pruning.

Metabolic regulation of Drosophila apoptosis through inhibitory phosphorylation of Dronc.

Structure of the Drosophila apoptosome at 6.9 å resolution.

Glial-derived prodegenerative signaling in the Drosophila neuromuscular system.

Necrosis-driven systemic immune response alters SAM metabolism through the FOXO-GNMT axis.

Structure of the apoptosome: mechanistic insights into activation of an initiator caspase from Drosophila.

Dark and Dronc activation in Drosophila melanogaster.