Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Combined Automated Annotation using Multiple IEA Methods
YeastPathways to GO-CAM conversion
Metabolic-flux and network analysis in fourteen hemiascomycetous yeasts.
The amino acid sequence of the aspartate aminotransferase from baker's yeast (Saccharomyces cerevisiae).
Cytosolic aspartate aminotransferase moonlights as a ribosome-binding modulator of Gcn2 activity during oxidative stress.
-
Aat2 restrains peroxide-induced Gcn2/eIF2alpha activation and translational repression independently of catalytic activity; untreated translation is similar.
"Polysome profile analysis revealed that translation was similar in untreated aat2∆ and wild-type (parent) cells, but ribosome run-off caused by addition of H2O2 was more acute in aat2∆ at lower concentrations of peroxide"
Cytosolic aspartate aminotransferase encoded by the AAT2 gene is targeted to the peroxisomes in oleate-grown Saccharomyces cerevisiae.
Mutations that cause threonine sensitivity identify catalytic and regulatory regions of the aspartate kinase of Saccharomyces cerevisiae.
Autophagy sustains glutamate and aspartate synthesis in Saccharomyces cerevisiae during nitrogen starvation.
UniProt entry P23542 (AAT2)
The evolution and role of the periplasmic asparaginase Asp3 in yeast.
-
The asparagine-assimilation pathway includes downstream conversion of aspartate to glutamate and oxaloacetate; this supports a secondary AspAT contribution, not direct asparagine hydrolysis.
"Intracellular aspartate is converted to glutamate and oxaloacetate, which are easily utilised by the cell through the central nitrogen metabolism."