Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Cell cycle progression of chronic lymphocytic leukemia cells is controlled by cyclin D2, cyclin D3, cyclin-dependent kinase (cdk) 4 and the cdk inhibitor p27.
Towards a proteome-scale map of the human protein-protein interaction network.
Increased p21 expression and complex formation with cyclin E/CDK2 in retinoid-induced pre-B lymphoma cell apoptosis.
Migratory localization of cyclin D2-Cdk4 complex suggests a spatial regulation of the G1-S transition.
Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.
The protein interaction landscape of the human CMGC kinase group.
Characterization of microRNA-29 family expression and investigation of their mechanistic roles in gastric cancer.
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.
A proteome-scale map of the human interactome network.
Widespread macromolecular interaction perturbations in human genetic disorders.
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Pooled-matrix protein interaction screens using Barcode Fusion Genetics.
Architecture of the human interactome defines protein communities and disease networks.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
A reference map of the human binary protein interactome.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases.
The AMBRA1 E3 ligase adaptor regulates the stability of cyclin D.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
A comprehensive two-hybrid analysis to explore the Legionella pneumophila effector-effector interactome.
Multimodal cell maps as a foundation for structural and functional genomics.
Growth suppression by p16ink4 requires functional retinoblastoma protein.
Identification of G1 kinase activity for cdk6, a novel cyclin D partner.
Cyclin E2, a novel human G1 cyclin and activating partner of CDK2 and CDK3, is induced by viral oncoproteins.
Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex
Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex
Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes
Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus
CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6
CDK6 inhibitors bind CDK6
CDK4 inhibitors bind CDK4