Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on curation of immunofluorescence data

Combined Automated Annotation using Multiple IEA Methods

The kinesin protein Kif7 is a critical regulator of Gli transcription factors in mammalian hedgehog signaling.

The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development.

Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling.

KIF7 mutations cause fetal hydrolethalus and acrocallosal syndromes.

Mutations in KIF7 link Joubert syndrome with Sonic Hedgehog signaling and microtubule dynamics.

Kif7 promotes hedgehog signaling in growth plate chondrocytes by restricting the inhibitory function of Sufu.

Kif7 regulates Gli2 through Sufu-dependent and -independent functions during skin development and tumorigenesis.

Positive and negative regulation of Gli activity by Kif7 in the zebrafish embryo.

The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment.

Altered chemomechanical coupling causes impaired motility of the kinesin-4 motors KIF27 and KIF7.

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.

OpenCell: Endogenous tagging for the cartography of human cellular organization.

P4HA2 hydroxylates SUFU to regulate the paracrine Hedgehog signaling and promote B-cell lymphoma progression.

Multimodal cell maps as a foundation for structural and functional genomics.

KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules