Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Automatic Gene Ontology annotation based on Rhea mapping
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Human tribbles, a protein family controlling mitogen-activated protein kinase cascades.
Interacting JNK-docking sites in MKK7 promote binding and activation of JNK mitogen-activated protein kinases.
Expression of the Bcl-2 protein BAD promotes prostate cancer growth.
A directed protein interaction network for investigating intracellular signal transduction.
Deciphering the Dynamic Interaction Profile of an Intrinsically Disordered Protein by NMR Exchange Spectroscopy.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases.
Enthalpy-Entropy Compensation in the Promiscuous Interaction of an Intrinsically Disordered Protein with Homologous Protein Partners.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Multimodal cell maps as a foundation for structural and functional genomics.
Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2.
JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension.
Phosphorylation of human JNKs by activated MKK4/MKK7
Fc epsilon receptor (FCERI) signaling
Phosphorylation of MEK4 by MEKK1
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
Activated TAK1 phosphorylates MKK4/MKK7
Anthrax lef cleaves target cell MAP2K4 (MEK4)
A docking site in MKK4 mediates high affinity binding to JNK MAPKs and competes with similar docking sites in JNK substrates.
Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms.
MLK-3 activates the SAPK/JNK and p38/RK pathways via SEK1 and MKK3/6.
UniProt entry P45985 (MP2K4_HUMAN)
Deep research report on MAP2K4 (falcon)