Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Automatic Gene Ontology annotation based on Rhea mapping
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Inhibitory phosphorylation of the APC regulator Hct1 is controlled by the kinase Cdc28 and the phosphatase Cdc14.
A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae.
Cks1 is required for G(1) cyclin-cyclin-dependent kinase activity in budding yeast.
A comprehensive two-hybrid analysis to explore the yeast protein interactome.
Functional organization of the yeast proteome by systematic analysis of protein complexes.
Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry.
Phosphorylation of the mitotic regulator Pds1/securin by Cdc28 is required for efficient nuclear localization of Esp1/separase.
The CLN3/SWI6/CLN2 pathway and SNF1 act sequentially to regulate meiotic initiation in Saccharomyces cerevisiae.
Yeast Cdk1 translocates to the plus end of cytoplasmic microtubules to regulate bud cortex interactions.
Control of landmark events in meiosis by the CDK Cdc28 and the meiosis-specific kinase Ime2.
Cyclin-B homologs in Saccharomyces cerevisiae function in S phase and in G2.
Recruitment of Cdc28 by Whi3 restricts nuclear accumulation of the G1 cyclin-Cdk complex to late G1.
Assigning function to yeast proteins by integration of technologies.
Cell cycle-dependent phosphorylation of the DNA polymerase epsilon subunit, Dpb2, by the Cdc28 cyclin-dependent protein kinase.
Clb6/Cdc28 and Cdc14 regulate phosphorylation status and cellular localization of Swi6.
DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1.
Cdk1-dependent regulation of the mitotic inhibitor Wee1.
Global analysis of protein phosphorylation in yeast.
Proteome survey reveals modularity of the yeast cell machinery.
The role of phosphorylation and the CDC28 protein kinase in cell cycle-regulated nuclear import of the S. cerevisiae transcription factor SWI5.
Cdk1 regulates centrosome separation by restraining proteolysis of microtubule-associated proteins.
Cyclin-dependent kinase directly regulates initiation of meiotic recombination.
A mechanism for cell-cycle regulation of MAP kinase signaling in a yeast differentiation pathway.
Cdk1 coordinates cell-surface growth with the cell cycle.
Protein arms in the kinetochore-microtubule interface of the yeast DASH complex.
Cyclin Cln3 is retained at the ER and released by the J chaperone Ydj1 in late G1 to trigger cell cycle entry.
The role of CDC28 and cyclins during mitosis in the budding yeast S. cerevisiae.
A cyclin B homolog in S. cerevisiae: chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosis.
Cdk1-dependent phosphorylation of Cdc13 coordinates telomere elongation during cell-cycle progression.
Cdk1/Cdc28-dependent activation of the major triacylglycerol lipase Tgl4 in yeast links lipolysis to cell-cycle progression.
Antagonistic regulation of Fus2p nuclear localization by pheromone signaling and the cell cycle.
Regulation of repair choice: Cdk1 suppresses recruitment of end joining factors at DNA breaks.
Processing of meiotic DNA double strand breaks requires cyclin-dependent kinase and multiple nucleases.
A global protein kinase and phosphatase interaction network in yeast.
Cdk phosphorylation of a nucleoporin controls localization of active genes through the cell cycle.
Cyclin-dependent kinase promotes formation of the synaptonemal complex in yeast meiosis.
Cks1, Cdk1, and the 19S proteasome collaborate to regulate gene induction-dependent nucleosome eviction in yeast.
SCFCdc4 enables mating type switching in yeast by cyclin-dependent kinase-mediated elimination of the Ash1 transcriptional repressor.
G1-specific cyclins of S. cerevisiae: cell cycle periodicity, regulation by mating pheromone, and association with the p34CDC28 protein kinase.
Phosphorylation-dependent regulation of the F-BAR protein Hof1 during cytokinesis.
Cdk1-dependent destruction of Eco1 prevents cohesion establishment after S phase.
Ase1p phosphorylation by cyclin-dependent kinase promotes correct spindle assembly in S. cerevisiae.
Mitotic role for the Cdc28 protein kinase of Saccharomyces cerevisiae.
Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation.
Cascades of multisite phosphorylation control Sic1 destruction at the onset of S phase.
Cdk1 promotes kinetochore bi-orientation and regulates Cdc20 expression during recovery from spindle checkpoint arrest.
Restriction of histone gene transcription to S phase by phosphorylation of a chromatin boundary protein.
Spatiotemporal regulation of Ipl1/Aurora activity by direct Cdk1 phosphorylation.
Cyclin-dependent kinase-dependent phosphorylation of Lif1 and Sae2 controls imprecise nonhomologous end joining accompanied by double-strand break resection.
Cdc28 kinase activity regulates the basal transcription machinery at a subset of genes.
Cdk1-dependent control of membrane-trafficking dynamics.
CDK-dependent Hsp70 Phosphorylation controls G1 cyclin abundance and cell-cycle progression.
Proteome-wide protein interaction measurements of bacterial proteins of unknown function.
Sequential primed kinases create a damage-responsive phosphodegron on Eco1.
Global analysis of cdc14 dephosphorylation sites reveals essential regulatory role in mitosis and cytokinesis.
Cdk1-dependent phosphorylation of Iqg1 governs actomyosin ring assembly prior to cytokinesis.
CDC28 phosphorylates Cac1p and regulates the association of chromatin assembly factor I with chromatin.
A family of cyclin homologs that control the G1 phase in yeast.
ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.
Enrichment of Cdk1-cyclins at DNA double-strand breaks stimulates Fun30 phosphorylation and DNA end resection.
Pachytene arrest and other meiotic effects of the start mutations in Saccharomyces cerevisiae.
Fimbrin phosphorylation by metaphase Cdk1 regulates actin cable dynamics in budding yeast.
The Yeast Cyclin-Dependent Kinase Routes Carbon Fluxes to Fuel Cell Cycle Progression.
Cyclin-Dependent Kinase Co-Ordinates Carbohydrate Metabolism and Cell Cycle in S. cerevisiae.
Clb6-Cdc28 Promotes Ribonucleotide Reductase Subcellular Redistribution during S Phase.
Phosphoregulation of Rad51/Rad52 by CDK1 functions as a molecular switch for cell cycle-specific activation of homologous recombination.
Subcellular localization of a protein kinase required for cell cycle initiation in Saccharomyces cerevisiae: evidence for an association between the CDC28 gene product and the insoluble cytoplasmic matrix.
The social and structural architecture of the yeast protein interactome.
Three additional genes required for deoxyribonucleic acid synthesis in Saccharomyces cerevisiae.
The selection of S. cerevisiae mutants defective in the start event of cell division.
Simian virus 40 large T antigen affects the Saccharomyces cerevisiae cell cycle and interacts with p34CDC28.
A new pair of B-type cyclins from Saccharomyces cerevisiae that function early in the cell cycle.
CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae.
Spindle pole body separation in Saccharomyces cerevisiae requires dephosphorylation of the tyrosine 19 residue of Cdc28.
Interaction between yeast Cdc6 protein and B-type cyclin/Cdc28 kinases.
Control of Saccharomyces cerevisiae filamentous growth by cyclin-dependent kinase Cdc28.
Falcon deep research for CDC28
-
Cdc28 is the single catalytic CDK subunit that, by exchanging cyclin partners and using docking motifs and Cks1 priming, triggers Start, replication, spindle assembly, chromosome segregation and mitotic exit.
"Cdc28 is the central catalytic engine of the budding-yeast division cycle. By changing cyclin partners and exploiting cyclin-docking motifs, Cks1-dependent phospho-priming, localization, and kinase/phosphatase feedback, the same catalytic subunit triggers Start, DNA replication, spindle assembly, chromosome segregation, and mitotic exit."