Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
TreeGrafter-generated GO annotations
Combined Automated Annotation using Multiple IEA Methods
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Combines InterPro, UniRule, Rhea, EC, and PANTHER evidence
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Source of primary functional annotations including GO:0004149, GO:0006099, GO:0045252
UniProt entry for sucB dihydrolipoyllysine-residue succinyltransferase
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TrEMBL entry (unreviewed) with EC 2.3.1.61
"Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex"
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Contains lipoyl-binding domain (2-77) and PSBD domain (143-180)
"PROSITE; PS50968; BIOTINYL_LIPOYL"
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Forms 24-mer structural core of OGDH complex
"Forms a 24-polypeptide structural core with octahedral symmetry"
Methylobacterium genome sequences: a reference blueprint to investigate microbial metabolism of C1 compounds from natural and industrial sources.
Deep research report on sucB E2 component of OGDH complex
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E2o (sucB) forms the multimeric core scaffold that organizes E1o and E3 for efficient substrate channeling
"The E2o subunit (sucB) forms the multimeric core scaffold that organizes E1o and E3 for efficient substrate channeling"
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In bacteria OGDHc operates in the cytosol as a soluble megacomplex
"in bacteria it operates in the cytosol as a soluble megacomplex"
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OGDHc converts 2-oxoglutarate + CoA + NAD+ to succinyl-CoA + CO2 + NADH
"The OGDHc converts 2-oxoglutarate + CoA + NAD+ → succinyl-CoA + CO2 + NADH"