UniProt assigns Q88NB8 the MoaD-dependent molybdopterin synthase reaction, EC 2.8.1.12, and a 2:2 MoaD-MoaE complex.
"CC -!- CATALYTIC ACTIVITY:
CC Reaction=2 [molybdopterin-synthase sulfur-carrier protein]-C-terminal-
CC Gly-aminoethanethioate + cyclic pyranopterin phosphate + H2O =
CC molybdopterin + 2 [molybdopterin-synthase sulfur-carrier protein]-C-
CC terminal Gly-Gly + 2 H(+); Xref=Rhea:RHEA:26333, Rhea:RHEA-
CC COMP:12202, Rhea:RHEA-COMP:19907, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:58698, ChEBI:CHEBI:59648,
CC ChEBI:CHEBI:90778, ChEBI:CHEBI:232372; EC=2.8.1.12;
CC Evidence={ECO:0000256|ARBA:ARBA00049878};
CC -!- PATHWAY: Cofactor biosynthesis; molybdopterin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005046}.
CC -!- SUBUNIT: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also
CC stable as homodimer. The enzyme changes between these two forms during
CC catalysis. {ECO:0000256|ARBA:ARBA00026066}."