GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:12620389
Novel raf kinase protein-protein interactions found by an exhaustive yeast two-hybrid analysis.
PMID:14718356
Relationship between carbamoyl-phosphate synthetase genotype and systemic vascular function.
PMID:15161933
Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.
PMID:15897806
Release of the mitochondrial enzyme carbamoyl phosphate synthase under septic conditions.
PMID:18063578
The layered structure of human mitochondrial DNA nucleoids.
PMID:1840546
Cloning and sequence of a cDNA encoding human carbamyl phosphate synthetase I: molecular analysis of hyperammonemia.
PMID:20031578
Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: a genome-wide evaluation of 13 974 participants in the Women's Genome Health Study.
PMID:20618440
Proteomic and biochemical analysis of 14-3-3-binding proteins during C2-ceramide-induced apoptosis.
PMID:21120950
Molecular defects in human carbamoy phosphate synthetase I: mutational spectrum, diagnostic and protein structure considerations.
PMID:23649895
Molecular characterization of carbamoyl-phosphate synthetase (CPS1) deficiency using human recombinant CPS1 as a key tool.
PMID:24813853
Understanding carbamoyl phosphate synthetase (CPS1) deficiency by using the recombinantly purified human enzyme: effects of CPS1 mutations that concentrate in a central domain of unknown function.
PMID:26592762
Structure of human carbamoyl phosphate synthetase: deciphering the on/off switch of human ureagenesis.
PMID:34800366
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.
PMID:6249820
Human carbamylphosphate synthetase I. Stabilization, purification, and partial characterization of the enzyme from human liver.
PMID:7416778
Detection of carbamyl phosphate synthetase 1 deficiency using duodenal biopsy samples.
PMID:8486760
Carbamyl phosphate synthetase I deficiency. One base substitution in an exon of the CPS I gene causes a 9-basepair deletion due to aberrant splicing.
PMID:9711878
Prenatal diagnosis of carbamoyl phosphate synthetase I deficiency by identification of a missense mutation in CPS1.
Reactome:R-HSA-70555
2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial]
Reactome:R-HSA-70635
Urea cycle
Reactome:R-HSA-9955504
SIRT5 deglutarylates CPS1
Reactome:R-HSA-9955543
CPS1 variants don't synthesize carbamoyl phosphate
Reactome:R-HSA-9959874
CPS1 gene expression