GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000033
Annotation inferences using phylogenetic trees
PMID:17897319
Integral and associated lysosomal membrane proteins.
PMID:20613862
A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia.
PMID:22022230
The fifth adaptor protein complex.
PMID:23167973
Adaptor protein complexes AP-4 and AP-5: new players in endosomal trafficking and progressive spastic paraplegia.
PMID:23825025
Interaction between AP-5 and the hereditary spastic paraplegia proteins SPG11 and SPG15.
PMID:25416956
A proteome-scale map of the human interactome network.
PMID:26085577
Loss of AP-5 results in accumulation of aberrant endolysosomes: defining a new type of lysosomal storage disease.
PMID:27392064
Human Immunodeficiency Virus Type 2 (HIV-2) Gag Is Trafficked in an AP-3 and AP-5 Dependent Manner.
PMID:29381698
Role of the AP-5 adaptor protein complex in late endosome-to-Golgi retrieval.
PMID:33464297
Rag GTPases and phosphatidylinositol 3-phosphate mediate recruitment of the AP-5/SPG11/SPG15 complex.
PMID:33961781
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
PMID:40081374
Bi-allelic variants in three genes encoding distinct subunits of the vesicular AP-5 complex cause hereditary macular dystrophy.
PMID:40175557
Structural basis for membrane remodeling by the AP5-SPG11-SPG15 complex.
PMID:41830174
Bi-allelic variants in AP5Z1 and AP5B1 lead to retinal degeneration.
PMID:42568187
The AP5B1 p.Leu785Pro variant is a frequent cause of late-onset macular dystrophy with variable extraocular manifestations.
file:human/AP5B1/AP5B1-uniprot.txt
UniProtKB Q2VPB7 (AP5B1_HUMAN) flat file
file:human/AP5B1/AP5B1-deep-research-affinage.md
Affinage mechanistic annotation for AP5B1 (human)
file:human/AP5B1/AP5B1-bioinformatics/RESULTS.md
AP5B1 (beta-5 adaptin): does it carry the beta-adaptin clathrin-binding apparatus?