LRO1 (YNR008W, P40345) notes

Evidence journal (UniProt and cached publications; no paid deep research).

• Lro1 is an LCAT-related PDAT that transfers an acyl chain from PC/PE to DAG. PMID:10747858 PMID:10829075
• PDAT forms a branch distinct from LCAT. PMID:10829075 For this reason the CACAO ISO row (with/from mouse LCAT P16301) is removed as mis-sourced; the activity itself is accepted on the IDA/IMP/EXP rows.
• Substrate preference: the sn-2 acyl of PE. PMID:18037386
• Lro1 is a type II ER membrane protein with a luminal catalytic domain. [UniProt:P40345 "type II membrane protein {ECO:0000269|PubMed:22446555}"] It relocates to the inner nuclear membrane. PMID:31422915
• Curation decisions: PDAT activity, TAG biosynthesis, and the ER membrane/INM are core. Lipid storage, ceramide, phospholipid homeostasis, LD and cytoplasm are non-core. The RCA cytosol row is removed.