GO_REF:0000002

Gene Ontology annotation through association of InterPro records with GO terms

GO_REF:0000117

Electronic Gene Ontology annotations created by ARBA (Association-Rule-Based Annotator)

file:AILME/A0A7N5KEZ3_AILME/A0A7N5KEZ3_AILME-uniprot.txt

UniProt record for A0A7N5KEZ3 (giant panda uncharacterized protein)

The TrEMBL entry is an uncharacterized 419 aa protein with the Keratin keyword and is assigned Pfam PF13885 (Keratin_B2_2), InterPro IPR002494 (KAP), and PANTHER PTHR21523:SF14; it carries two IEA GO annotations, keratin filament (InterPro) and cytosol (ARBA).

PMID:29797269

Trichocyte Keratin-Associated Proteins (KAPs).

In trichocyte (hard) keratins, keratin intermediate filaments are embedded in a matrix of keratin-associated proteins (KAPs) that organize the filaments into macrofibrils and link them to one another, stabilized predominantly by intramolecular disulfide bonds, conferring the mechanical properties of hair, wool, hoof, horn, claw, baleen and quill.

PMID:12895003

Characterization of human keratin-associated protein 1 family members.

Keratin-associated proteins form the cross-linked network of the keratin intermediate filament proteins that support hair fibers; high-sulfur KAP family members are characterized by double cysteine-containing pentapeptide repeats, the same repeat architecture seen in this giant panda protein.