Fer2LCH (CG1469, Q9VA83) notes

2026-10-09 review session (module dmel_ferritin_complex)

• Deep research: Fer2LCH-deep-research-falcon.md. L chain nucleates the mineral core; H chain has the
  ferroxidase center [Fer2LCH-deep-research-falcon.md "These observations do not establish that Fer2LCH itself oxidizes iron."].
• PMID:17603097
• LCH predominant subunit; no IRE in its mRNA PMID:11804801.
• Same iron absorption/detoxification genetics as Fer1HCH PMID:23064556.

Decisions

• Shared complex/location/process decisions mirror Fer1HCH (same module).
• iron ion import across plasma membrane -> MODIFY to GO:0160179 intestinal iron absorption.
• ferrous iron binding (IDA) -> KEEP_AS_NON_CORE (complex-level; L chain lacks ferroxidase site).
• No ferroxidase annotation exists for Fer2LCH and none proposed.
• Core MF: GO:0140315 iron ion sequestering activity, in ferritin complex.