Use of the ND evidence code for Gene Ontology (GO) terms
Annotation inferences using phylogenetic trees
Electronic Gene Ontology annotations created by ARBA machine learning models
Molecular characterization of mammalian dicarbonyl/L-xylulose reductase and its localization in kidney.
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Purified mammalian DCXR proteins reduce alpha-dicarbonyls and interconvert xylitol and L-xylulose; this supports ortholog-based chemistry rather than a zebrafish assay.
"homotetramers with NADPH-linked reductase activity for alpha-dicarbonyl
compounds, catalyzed the oxidoreduction between xylitol and l-xylulose"
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The characterized L-xylulose reaction belongs to uronate metabolism, providing the basis for broad glucose-metabolism association.
"which is involved in the uronate cycle
of glucose metabolism"
Conservation of the DCXR catalytic site
UniProt record identifying the bacterial FabG function donor
Frozen exact-input ProtNLM output and UniProt sequence for Q567K5