GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:11847227
Functional overlap between retinitis pigmentosa 2 protein and the tubulin-specific chaperone cofactor C.
PMID:12417528
Localization in the human retina of the X-linked retinitis pigmentosa protein RP2, its homologue cofactor C and the RP2 interacting protein Arl3.
PMID:16169070
A human protein-protein interaction network: a resource for annotating the proteome.
PMID:16525022
Arl2 and Arl3 regulate different microtubule-dependent processes.
PMID:17646400
Functional dissection of Rab GTPases involved in primary cilium formation.
PMID:18588884
Specificity of Arl2/Arl3 signaling is mediated by a ternary Arl3-effector-GAP complex.
PMID:19056867
Large-scale proteomics and phosphoproteomics of urinary exosomes.
PMID:20106869
The retinitis pigmentosa protein RP2 links pericentriolar vesicle transport between the Golgi and the primary cilium.
PMID:22085962
An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium.
PMID:26455799
The Interaction of CCDC104/BARTL1 with Arl3 and Implications for Ciliary Function.
PMID:27173435
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
PMID:28514442
Architecture of the human interactome defines protein communities and disease networks.
PMID:30257685
Modifying Rap1-signalling by targeting Pde6δ is neuroprotective in models of Alzheimer's disease.
PMID:30269812
ARL3 Mutations Cause Joubert Syndrome by Disrupting Ciliary Protein Composition.
PMID:32296183
A reference map of the human binary protein interactome.
PMID:33961781
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
PMID:35271311
OpenCell: Endogenous tagging for the cartography of human cellular organization.
PMID:40205054
Multimodal cell maps as a foundation for structural and functional genomics.
PMID:8034651
ADP-ribosylation factor (ARF)-like 3, a new member of the ARF family of GTP-binding proteins cloned from human and rat tissues.
Reactome:R-HSA-5624130
Myristoylated NPHP3 translocates into the ciliary membrane
Reactome:R-HSA-5624133
ARL3:GTP binds the UNC119B complex
Reactome:R-HSA-5638004
RP2 binds ARL3:GTP:UNC119B
Reactome:R-HSA-5638006
ARL3 hydrolyzes GTP
Reactome:R-HSA-5638007
RP2 activates the GTPase activity of ARL3
Reactome:R-HSA-5638016
RP2:ARL3:GDP:UNC119B dissociates
file:human/ARL3/ARL3-deep-research-falcon.md
Falcon deep research report for ARL3 (human)