GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:11441007
PDZ domain protein GIPC interacts with the cytoplasmic tail of melanosomal membrane protein gp75 (tyrosinase-related protein-1).
PMID:19841138
AP-1 and KIF13A coordinate endosomal sorting and positioning during melanosome biogenesis.
PMID:21291857
Interactions between GIPC-APPL and GIPC-TRP1 regulate melanosomal protein trafficking and melanogenesis in human melanocytes.
PMID:21996312
Oculocutaneous albinism type 3: a Japanese girl with novel mutations in TYRP1 gene.
PMID:32296183
A reference map of the human binary protein interactome.
PMID:36115835
Quantitative fragmentomics allow affinity mapping of interactomes.
Reactome:R-HSA-5662702
Melanin biosynthesis
Reactome:R-HSA-8878581
TYRP1 oxidises DHICA to IQCA
Reactome:R-HSA-9824593
MITF-M-dependent TYRP1 gene expression
PMID:28661582
Structure of Human Tyrosinase Related Protein 1 Reveals a Binuclear Zinc Active Site Important for Melanogenesis.
PMID:18334748
Generation and characterization of a therapeutic human antibody to melanoma antigen TYRP1.
PMID:39308793
TYRP1 directed CAR T cells control tumor progression in preclinical melanoma models.
PMID:16704458
Oculocutaneous albinism with TYRP1 gene mutations in a Caucasian patient.
file:human/TYRP1/TYRP1-uniprot.txt
UniProtKB entry P17643 (TYRP1_HUMAN), 5,6-dihydroxyindole-2-carboxylic acid oxidase