Accession: Q9VLD6 (FBgn0032105).
Deep research: borr-deep-research-falcon.md (falcon; the wrapper logged a 600 s timeout but the run completed and wrote the file). Important addition: Borr acts in acentrosomal female meiosis (oocytes): a Borr-INCENP fusion rescues bipolar and central spindle assembly after INCENP depletion, and borr RNAi increases homolog mono-orientation; 14-3-3 binding of phospho-Borr restrains CPC microtubule association. Borr is therefore absent only from male meiosis, so general spindle-midzone rows are kept general and only the male-meiosis-attributed and mitosis-specific rows are made specific.
Literature journal
Decisions
- Meiotic spindle midzone IDA (PMID:18268101) modified to mitotic spindle midzone: the paper states Borr is absent from the male meiotic midzone.
- Spindle (UniProt) modified to spindle midzone; spindle midzone IDA from the mitotic-cell paper (PMID:16224046) modified to mitotic spindle midzone; spindle midzone IBA accepted as-is because Borr also acts in oocyte meiosis.
- Protein binding (Shrb) removed: no informative ESCRT-III binding term exists.
Female meiosis provenance (from deep research; primary papers not cached)
- Borr-INCENP fusion rescue in oocytes (Wang et al. 2021, J Cell Biol, as summarized) [file:DROME/borr/borr-deep-research-falcon.md "Borr–INCENP fusion** supported chromosome-dependent assembly of a bipolar spindle and central spindle in INCENP-depleted oocytes"].
- 14-3-3 binding of phospho-Borr [file:DROME/borr/borr-deep-research-falcon.md "Purified Borr residues 113–221 bound 14-3-3ε after phosphorylation by PKD2"].
- The meiotic spindle midzone row from PMID:18268101 was modified because that male-meiosis paper shows Borr absent from the meiotic midzone; a meiotic midzone pool in oocytes is plausible but would need an oocyte reference.