Gene Ontology annotation through association of InterPro records with GO terms
Use of the ND evidence code for Gene Ontology (GO) terms
Annotation inferences using phylogenetic trees
Combined Automated Annotation using Multiple IEA Methods
Disruption of the sporulation-specific gene spiA in Dictyostelium discoideum leads to spore instability.
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spiA is expressed specifically in prespore cells and spores during culmination, the terminal stage of development.
"The spiA gene of Dictyostelium is expressed specifically in prespore cells and spores during culmination, the final stage of development during which prespore and prestalk cells undergo terminal differentiation to form spores and stalk."
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The Dd31 protein is associated with the inner face of the spore coat in a detergent-resistant manner.
"Dd31 is associated with the inner face of spore coat fragments in a detergent-resistant manner."
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spiA-null spores develop and look normal but lose viability far more rapidly with age than wild-type spores, and reintroducing spiA restores spore stability.
"Mutant spores have normal viability when assayed soon after the completion of development, but, as the spiA- spores age, they lose viability more rapidly than those of the spiA+ parent."
Leaps and lulls in the developmental transcriptome of Dictyostelium discoideum.
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spiA is a sporulation marker whose transcript is up-regulated during culmination between 18 and 24 h of development.
"spiA was up-regulated between 18 h and 20 h, and accumulated rapidly through 24 h."
OpenScientist function-assignment analysis of the SpiA SCAMP trafficking hypothesis